The average salary for a Registered Nurse in Santa Ana is 108,213 $ per year on a 40-hour full-time equivalent, or 9,018 $ gross per month and 52.03 $ gross per hour. The reported full-time salary range is 72,000 $ to 166,667 $. The analysis is based on 34 salary reports from workers and employers in Santa Ana. Part-time salaries are proportionally converted to 40 weekly hours so the values are comparable.
| Date | Job title | Weekly hours | Reported gross/year | Normalized to 40h/year | Gross/month 40h | Gross/hour 40h | Note |
|---|---|---|---|---|---|---|---|
| 06/15/2026 | Nurse Manager - Surgical Services | 45.0 h | 160,000 $ | 142,222 $ | 11,852 $ | 68.38 $ | In 2026 I am the nurse manager for surgical services at a large hospital. I work around 45 hours per week overseeing multiple OR teams, scheduling, and operational budgets. |
| 06/02/2026 | Registered Nurse - Infusion Center (Part-time) | 30.0 h | 64,000 $ | 85,333 $ | 7,111 $ | 41.03 $ | In 2026 I work part-time at an oncology infusion center about 30 hours per week. I administer infusions and educate patients but don't have supervisory responsibilities. |
| 05/30/2026 | Per Diem Registered Nurse - Emergency | 18.0 h | 68,000 $ | 151,111 $ | 12,593 $ | 72.65 $ | I work per diem in the ED in 2026 averaging about 18 hours per week. High hourly rates for per diem shifts mean good earnings despite part-time hours. |
| 04/09/2026 | Registered Nurse - Psychiatric Partial Hospitalization | 40.0 h | 99,000 $ | 99,000 $ | 8,250 $ | 47.60 $ | I work full-time in a psychiatric partial hospitalization program in 2026. I handle group facilitation, medication monitoring, and care planning at 40 hours per week. |
| 03/21/2026 | Registered Nurse - Telemetry | 38.0 h | 113,000 $ | 118,947 $ | 9,912 $ | 57.19 $ | I have been a telemetry RN at a tertiary care center since 2024 and reported this salary in 2026 after receiving experience-based raises. I work approximately 38 hours per week. |
| 02/28/2026 | Senior RN - Cardiac Stepdown | 40.0 h | 141,000 $ | 141,000 $ | 11,750 $ | 67.79 $ | I was a senior RN in the cardiac stepdown unit in early 2026 with over ten years of experience. Full-time 40 hours with preceptor duties and specialty certifications included. |
| 01/12/2026 | Lead Registered Nurse - Outpatient Surgery | 42.0 h | 149,000 $ | 141,905 $ | 11,825 $ | 68.22 $ | I am the lead RN for an outpatient surgery unit in 2026, working about 42 hours per week. I coordinate nurses across multiple OR suites and handle advanced scheduling duties. |
| 10/06/2025 | Nurse Educator (Staff Development) | 40.0 h | 129,000 $ | 129,000 $ | 10,750 $ | 62.02 $ | In 2025 I was hired as a nurse educator for a hospital system. Full-time 40 hours with responsibilities for onboarding, competency assessment, and in-service training. |
| 07/29/2025 | Travel Nurse - Critical Care | 36.0 h | 150,000 $ | 166,667 $ | 13,889 $ | 80.13 $ | I accepted several travel critical care contracts in 2025 and averaged 36 hours per week. The higher pay reflects agency rates and high-demand assignments that year. |
| 05/11/2025 | Registered Nurse - Ambulatory Surgery Center | 40.0 h | 118,500 $ | 118,500 $ | 9,875 $ | 56.97 $ | I worked full-time in an ambulatory surgery center in 2025 as an experienced RN. My responsibilities included pre-op assessment and PACU care, 40 hours per week. |
| 03/03/2025 | Registered Nurse - Case Management (Large Hospital) | 40.0 h | 122,000 $ | 122,000 $ | 10,167 $ | 58.65 $ | I moved into RN case management at a major health system in 2025. Full-time 40 hours, working on complex discharges and care coordination with a larger team. |
| 01/20/2025 | Registered Nurse - Private Duty (Self-employed) | 28.0 h | 68,000 $ | 97,143 $ | 8,095 $ | 46.70 $ | I worked privately as a self-employed private-duty RN in 2025 caring for one-on-one patients in the community. I averaged 28 hours per week and handled billing and scheduling myself. |
| 08/12/2024 | Registered Nurse - Pediatric ICU (Part-time) | 30.0 h | 72,000 $ | 96,000 $ | 8,000 $ | 46.15 $ | In 2024 I worked part-time in the PICU after returning from maternity leave. I averaged 30 hours per week and kept a clinical role without administrative duties. |
| 05/24/2024 | Nurse Supervisor (Rehab Unit) | 44.0 h | 136,000 $ | 123,636 $ | 10,303 $ | 59.44 $ | I worked as a nurse supervisor for a rehabilitation unit in 2024. I averaged 44 hours weekly handling staffing, QA, and interdepartmental coordination. |
| 01/16/2024 | Registered Nurse - Float Pool | 38.0 h | 98,000 $ | 103,158 $ | 8,596 $ | 49.60 $ | I worked in a hospital float pool in 2024 rotating through med-surg, telemetry, and ED. Full-time 38 hours with shift differentials for nights and weekends. |
| 10/01/2023 | Registered Nurse - Oncology | 40.0 h | 115,000 $ | 115,000 $ | 9,583 $ | 55.29 $ | I was an oncology RN in 2023 at a specialty infusion center. Full-time 40 hours; my role included chemotherapy administration and patient education, plus certification pay. |
| 06/18/2023 | Charge Nurse - Emergency Department | 42.0 h | 140,500 $ | 133,810 $ | 11,151 $ | 64.33 $ | In 2023 I was the charge nurse in a very busy ED at a large county hospital. I worked about 42 hours weekly and had significant leadership and triage responsibilities. |
| 02/14/2023 | Registered Nurse - Behavioral Health | 36.0 h | 76,000 $ | 84,444 $ | 7,037 $ | 40.60 $ | I worked as a behavioral health RN at a community mental health facility in 2023. Full-time 36 hours per week with a mix of direct patient care and documentation. |
| 11/07/2022 | Senior Registered Nurse - ICU | 40.0 h | 132,000 $ | 132,000 $ | 11,000 $ | 63.46 $ | As a senior ICU RN in 2022 I had seven years of critical care experience. Full-time 40-hour role with mentorship responsibilities and specialty certifications. |
| 08/29/2022 | Registered Nurse - Telehealth (Part-time) | 25.0 h | 54,000 $ | 86,400 $ | 7,200 $ | 41.54 $ | In 2022 I worked part-time providing telehealth nursing for a startup clinic. I averaged 25 hours per week and handled follow-up calls and remote triage. |
| 03/10/2022 | Operating Room RN | 40.0 h | 98,000 $ | 98,000 $ | 8,167 $ | 47.12 $ | I worked full-time in the OR in 2022 at a large urban hospital. I had advanced perioperative training; my role was staff RN with pre-op and circulating responsibilities. |
| 10/21/2021 | Nurse Manager (Outpatient Services) | 42.0 h | 125,000 $ | 119,048 $ | 9,921 $ | 57.23 $ | In 2021 I was promoted to nurse manager for outpatient services at a medium-sized health system. I worked roughly 42 hours per week, handling scheduling, budgets, and staff oversight. |
| 07/08/2021 | Registered Nurse - Pediatrics | 40.0 h | 90,000 $ | 90,000 $ | 7,500 $ | 43.27 $ | I worked full-time in pediatric acute care in 2021 at a regional children's unit. I had about five years of experience and worked 40 hours per week with weekend rotation. |
| 05/02/2021 | Registered Nurse - Home Health (Self-employed) | 30.0 h | 62,000 $ | 82,667 $ | 6,889 $ | 39.74 $ | I started my own private home health business in 2021 working as a self-employed RN. I averaged 30 hours per week doing assessments and coordinating care for a small panel of patients. |
| 12/15/2020 | Travel Nurse - Emergency | 36.0 h | 118,000 $ | 131,111 $ | 10,926 $ | 63.03 $ | I took a travel ER contract in late 2020. I averaged 36 hours per week; agency pay and shift differentials significantly increased my annual income for that contract. |
| 11/27/2020 | ICU Registered Nurse (Staff) | 40.0 h | 106,000 $ | 106,000 $ | 8,833 $ | 50.96 $ | During the 2020 surge I was an ICU RN at a large hospital. Full-time 40 hours with heavy overtime; compensation reflected hazard pay adjustments that year. |
| 03/18/2020 | Registered Nurse - Clinic (Part-time) | 20.0 h | 36,000 $ | 72,000 $ | 6,000 $ | 34.62 $ | Part-time clinic RN in 2020 at a small primary care practice. I worked 20 hours per week and handled triage calls and procedures during clinic hours. |
| 12/02/2019 | Charge Nurse (Medical-Surgical) | 40.0 h | 88,000 $ | 88,000 $ | 7,333 $ | 42.31 $ | I was promoted to charge nurse in 2019 at a busy regional hospital. Full-time 40 hours with leadership duties overseeing a 20-bed unit, but not a formal manager. |
| 06/05/2019 | Registered Nurse - Case Manager | 35.0 h | 68,000 $ | 77,714 $ | 6,476 $ | 37.36 $ | I transitioned to a case management role in 2019 at a small outpatient clinic. Full-time 35 hours per week; administrative responsibilities increased but no direct reports. |
| 11/19/2018 | Labor & Delivery RN | 38.0 h | 78,000 $ | 82,105 $ | 6,842 $ | 39.47 $ | I worked as an L&D nurse at a private hospital starting in 2018. Full-time 38 hours per week with frequent on-call and overtime for deliveries. |
| 04/30/2018 | Travel Registered Nurse (ICU) | 36.0 h | 95,000 $ | 105,556 $ | 8,796 $ | 50.75 $ | I did a one-year travel contract in 2018 working ICU shifts through an agency. I averaged 36 hours per week; pay included higher hourly rates but I was on a W-2 travel contract. |
| 09/12/2017 | Emergency Department RN | 40.0 h | 82,000 $ | 82,000 $ | 6,833 $ | 39.42 $ | I was a mid-level ER RN at a large hospital in 2017. Full-time 40-hour schedule, nights and some weekend rotations. Worked there for three years before moving on. |
| 11/03/2016 | Staff Registered Nurse (Medical-Surgical) | 36.0 h | 70,000 $ | 77,778 $ | 6,481 $ | 37.39 $ | I'm an entry-level RN hired in 2016 at a mid-sized community hospital doing med-surg nights. I worked 36 hours per week as a full-time staff nurse with occasional mandatory overtime. |
| 08/22/2016 | Registered Nurse - Home Health | 24.0 h | 48,000 $ | 80,000 $ | 6,667 $ | 38.46 $ | I started part-time in home health in 2016 while finishing community college credits. I averaged 24 hours per week and billed as a W-2 employee of a small agency. |
The average salary for a Registered Nurse in Santa Ana is 108,213 $ per year on a 40-hour basis, or 9,018 $ gross per month.
Part-time and full-time reports are normalized to a 40-hour workweek so salary reports can be compared fairly.
You can find more comparisons on the profession overview for Registered Nurse and the city overview for Santa Ana. They show reported cities or jobs with their difference from the average.
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